AIsa positions itself above gateway-only competitors (OpenRouter, LiteLLM, Portkey) by combining four pillars: a Model Gateway (50+ models, OpenAI-compatible) covering GPT-5.4, Claude 4.6, Gemini 3.1 Pro plus Chinese LLMs (Qwen, DeepSeek, GLM, Kimi, MiniMax); a Skills marketplace; Machine-to-Machine APIs paid via Circle Nanopayments / HTTP 402 (Machine Payments Protocol); and a Foundry for cloud-hosted autonomous agents. CLI: npm install -g @aisa-one/cli. Backed by Tribe Capital, Draper Associates, Boost VC, Sats Ventures and Fenbushi Capital.

